Clomac Cream
Clobetasol Propionate 0.05% Cream — Super-Potent Topical Corticosteroid
| Composition | Clobetasol Propionate 0.05% Cream |
|---|---|
| Dosage Form | Topical Cream |
| Pack Type | Tube |
| Pack Size | 15 g / 30 g Tube |
| MRP | ₹ 79.5 |
| Therapy | Dermatology — Super-Potent Topical Corticosteroid (Class I) |
| Storage | Store below 30 °C in a dry place, away from direct heat and sunlight. |
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About Clomac Cream
Clomac Cream contains Clobetasol Propionate 0.05% — the most potent topical corticosteroid in clinical use (Class I, ultra-high potency). It is used for short-term treatment of severe, recalcitrant dermatoses including severe atopic eczema, psoriasis, discoid lupus erythematosus, lichen planus and severe contact dermatitis when less potent steroids have failed.
Maximum 2 weeks at a time, maximum 50 g per week, avoid face/groin/flexures, never under occlusion. Rebound flares are common after stopping; tapering to lower-potency steroid is recommended. The risk-benefit balance favours its short-term use only in genuinely severe disease.
Clomac Cream is manufactured by Trumac Healthcare under WHO-GMP conditions. Available for monopoly-based PCD pharma franchise and third-party manufacturing.
Indications
- Severe atopic dermatitis and eczema (short-term)
- Psoriasis (plaque, scalp)
- Discoid lupus erythematosus
- Lichen planus
- Severe contact and irritant dermatitis
- Other steroid-responsive severe dermatoses
Mechanism of Action
Clobetasol is a fluorinated glucocorticoid with very high glucocorticoid receptor affinity. It potently suppresses inflammatory gene transcription, immune cell infiltration and inflammatory cytokine production in the skin. The ultra-high potency comes at the cost of significantly higher systemic absorption and local atrophy risks compared with less potent steroids.
Dosage & Administration
Apply a thin layer to affected area once or twice daily. Maximum 2 weeks at a time, maximum 50 g per week. Do not use under occlusion. Avoid face, groin and flexures.
Side Effects
Skin atrophy, telangiectasia, striae, perioral dermatitis, acneiform eruptions, hypertrichosis. Systemic absorption can cause HPA-axis suppression (especially with prolonged use or large surface area). Tinea incognito if used on undiagnosed fungal infection.
Contraindications & Precautions
Hypersensitivity. Viral skin infections (herpes simplex, varicella). Bacterial or fungal skin infections (untreated). Rosacea, acne, perioral dermatitis. Use on face/groin/flexures (relative contraindication). Children (limit duration and area).
Storage
Store below 30 °C in a dry place, away from direct heat and sunlight.
Clomac Cream is available for monopoly-based PCD pharma franchise across India and for third-party manufacturing under your brand. WHO-GMP certified, with full visual-aid and promotional support. Become a Trumac franchise partner →
Frequently Asked Questions
What is Clomac Cream used for?
Clomac Cream contains Clobetasol Propionate 0.05%. Used as per the indications described above.
How should Clomac Cream be taken?
As directed by your physician. Complete the prescribed course.
Is Clomac Cream available for PCD pharma franchise?
Yes, Trumac Healthcare offers Clomac Cream on monopoly-based PCD pharma franchise and for third-party manufacturing.
How should Clomac Cream be stored?
Store below 30 °C in a dry place, protected from light and moisture.
Is Clomac Cream WHO-GMP certified?
Yes, manufactured in WHO-GMP and DCGI-compliant facilities.
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