Alfuzest-10 PR Tablet
Alfuzosin 10 mg Prolonged Release Tablets — Uroselective Alpha-1 Blocker
| Composition | Alfuzosin 10 mg (Prolonged Release) |
|---|---|
| Dosage Form | Prolonged Release Tablet |
| Pack Type | Blister |
| Pack Size | 10 x 15 Tablets |
| MRP | ₹ 1550 |
| Therapy | G.P. + Urology — Uroselective Alpha-1 Adrenergic Blocker |
| Storage | Store below 30 °C in a dry place, protected from light and moisture. |
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About Alfuzest-10 PR Tablet
Alfuzest-10 PR Tablet contains Alfuzosin Hydrochloride 10 mg in a once-daily prolonged-release matrix. Alfuzosin is a uroselective alpha-1 adrenergic antagonist used to treat the lower-urinary-tract symptoms (LUTS) of benign prostatic hyperplasia (BPH) — urinary hesitancy, weak stream, urgency, frequency and nocturia.
Because Alfuzosin preferentially blocks alpha-1A and alpha-1D receptors concentrated in the prostate, bladder neck and prostatic urethra, it relaxes urinary tract smooth muscle and improves urine flow without significant first-dose hypotension or systemic vasodilation seen with non-selective alpha-blockers.
Alfuzest-10 PR is manufactured by Trumac Healthcare under WHO-GMP conditions and is one of the company’s running-brand SKUs in the urology division. Available for monopoly-based PCD pharma franchise and third-party manufacturing.
Indications
- Lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH)
- Improvement of urinary flow rate in BPH
- Adjunctive therapy in acute urinary retention (AUR) management after catheterisation
- Symptomatic relief of prostatic obstruction
Mechanism of Action
Alfuzosin selectively antagonises post-synaptic alpha-1 adrenergic receptors in the prostate, bladder neck and prostatic urethra. This relaxes urinary tract smooth muscle tone, reduces bladder outlet obstruction and improves urinary flow without significant peripheral vasodilation, since uroselective alpha-1A/1D activity predominates over alpha-1B receptor activity.
Dosage & Administration
Adults: one 10 mg Prolonged Release tablet once daily, immediately after the same meal each day. Swallow whole — do not crush or chew. Re-evaluate clinical response after 4–6 weeks.
Side Effects
Dizziness, headache, fatigue, postural hypotension (especially with first dose), tachycardia, dry mouth, nausea, abdominal pain. Less common: syncope, intra-operative floppy iris syndrome (IFIS) during cataract surgery.
Contraindications & Precautions
Hypersensitivity to alfuzosin; history of postural hypotension; severe hepatic impairment; concomitant use of potent CYP3A4 inhibitors (ketoconazole, itraconazole, ritonavir). Inform ophthalmologist before cataract surgery. Not indicated in women or children.
Storage
Store below 30 °C in a dry place, protected from light and moisture.
Alfuzest-10 PR Tablet is available for monopoly-based PCD pharma franchise across India and for third-party manufacturing under your brand. WHO-GMP certified, with full visual-aid and promotional support. Become a Trumac franchise partner →
Frequently Asked Questions
What is Alfuzest-10 PR Tablet used for?
Alfuzest-10 PR Tablet contains Alfuzosin 10 mg Prolonged Release and is used to treat the urinary symptoms of benign prostatic hyperplasia (BPH) — hesitancy, weak stream, urgency, frequency and nocturia.
When should Alfuzest-10 PR be taken?
Take one tablet once daily, immediately after the same meal each day. Swallow whole — do not crush or chew the prolonged-release tablet.
Is Alfuzest-10 PR available for PCD pharma franchise?
Yes, Trumac Healthcare offers Alfuzest-10 PR Tablet on monopoly-based PCD pharma franchise across India, and for third-party manufacturing.
How should Alfuzest-10 PR Tablet be stored?
Store below 30 °C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Is Alfuzest-10 PR WHO-GMP certified?
Yes, Alfuzest-10 PR Tablet is manufactured in WHO-GMP and DCGI-compliant facilities.
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