Cildir-10 Tablet
Cilnidipine 10 mg Tablets — Dual L/N-Type Calcium Channel Blocker for Hypertension
| Composition | Cilnidipine 10 mg |
|---|---|
| Dosage Form | Tablet |
| Pack Type | Alu-Alu Blister |
| Pack Size | 10 x 10 Tablets |
| MRP | ₹ 995 |
| Therapy | Cardiac + Diabetic — Dual L-type / N-type Calcium Channel Blocker |
| Storage | Store below 30 °C in a dry place, protected from light and moisture. |
📱 WhatsApp Enquiry📞 Call: +919041677932
About Cildir-10 Tablet
Cildir-10 Tablet contains Cilnidipine 10 mg — a unique dihydropyridine calcium channel blocker that inhibits both L-type and N-type calcium channels. The N-type calcium channel inhibition (in sympathetic nerve terminals) provides additional sympathetic suppression and reduction in reflex tachycardia compared with classical L-type-only CCBs like amlodipine.
This dual mechanism translates into clinical advantages: less peripheral oedema, reduced reflex tachycardia, improved renal protection (particularly in diabetic nephropathy with proteinuria), and better suppression of sympathetic overactivity. Cilnidipine is particularly suited to hypertensive patients with diabetes, CKD or those experiencing palpitations on amlodipine.
Cildir-10 is manufactured by Trumac Healthcare under WHO-GMP conditions. Available for monopoly-based PCD pharma franchise and third-party manufacturing — a specialty cardiology SKU.
Indications
- Essential hypertension
- Hypertension with diabetes mellitus
- Hypertension with chronic kidney disease and proteinuria
- Hypertension with sympathetic overactivity
- Patients with oedema or tachycardia on amlodipine
Mechanism of Action
Cilnidipine blocks both L-type calcium channels in vascular smooth muscle (producing vasodilation) and N-type calcium channels in sympathetic nerve terminals (reducing noradrenaline release). The dual blockade produces blood pressure reduction with less reflex tachycardia and reduced renal afferent arteriolar resistance — beneficial in diabetic nephropathy.
Dosage & Administration
Adults: 5–10 mg once daily, taken at the same time each day. Titrate based on response. Maximum 20 mg/day.
Side Effects
Headache, flushing, dizziness, peripheral oedema (less than amlodipine), palpitations (less than other CCBs). Rare: gingival hyperplasia.
Contraindications & Precautions
Hypersensitivity to cilnidipine or other dihydropyridines. Severe aortic stenosis. Cardiogenic shock. Pregnancy and breastfeeding.
Storage
Store below 30 °C in a dry place, protected from light and moisture.
Cildir-10 Tablet is available for monopoly-based PCD pharma franchise across India and for third-party manufacturing under your brand. WHO-GMP certified, with full visual-aid and promotional support. Become a Trumac franchise partner →
Frequently Asked Questions
What is Cildir-10 Tablet used for?
Cildir-10 Tablet contains Cilnidipine 10 mg. Used as per its therapeutic indication described above.
How should Cildir-10 Tablet be taken?
As directed by your physician. Complete the prescribed course; do not stop early or self-adjust dose.
Is Cildir-10 Tablet available for PCD pharma franchise?
Yes, Trumac Healthcare offers Cildir-10 Tablet on monopoly-based PCD pharma franchise and for third-party manufacturing.
How should Cildir-10 Tablet be stored?
Store below 30 °C in a dry place, protected from light and moisture.
Is Cildir-10 Tablet WHO-GMP certified?
Yes, manufactured in WHO-GMP and DCGI-compliant facilities.
Related Products