Razium-40 DSR Capsule
Rabeprazole 40 mg + Domperidone 30 mg SR Capsules
| Composition | Rabeprazole 40 mg + Domperidone 30 mg (Sustained Release) |
|---|---|
| Dosage Form | Sustained Release Capsule |
| Pack Type | Alu-Alu Blister |
| Pack Size | 10 x 10 Capsules |
| MRP | ₹ 1950 |
| Therapy | Gastroenterology — High-Dose PPI + Prokinetic SR |
| Storage | Store below 30 °C in a dry place, protected from light and moisture. |
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About Razium-40 DSR Capsule
Razium-40 DSR Capsule combines high-dose Rabeprazole 40 mg with Domperidone 30 mg SR — for refractory GERD with delayed gastric emptying. Premium combination for severe cases unresponsive to standard 20 mg + 30 mg therapy.
Manufactured by Trumac Healthcare under WHO-GMP. Available for monopoly-based PCD pharma franchise and third-party manufacturing.
Indications
- Refractory GERD with bloating
- Severe functional dyspepsia
- Diabetic gastroparesis with severe reflux
Mechanism of Action
Rabeprazole irreversibly inhibits gastric H+/K+ ATPase (proton pump) — markedly suppressing both basal and stimulated acid secretion. Faster onset (within 1 hour) and less CYP2C19 dependence than Omeprazole. Domperidone is peripheral D2 receptor antagonist enhancing GI motility, accelerating gastric emptying, increasing LOS tone without crossing BBB.
Dosage & Administration
Adults: 1 capsule once daily before breakfast.
Side Effects
Headache, diarrhoea, abdominal pain. Long-term: B12 deficiency, hypomagnesaemia, fracture risk, C. difficile colitis. Hyperprolactinaemia, QT prolongation (Domperidone — short-term use).
Contraindications & Precautions
Hypersensitivity. Caution in severe hepatic impairment. Prolactinoma, QT prolongation.
Storage
Store below 30 °C in a dry place, protected from light and moisture.
Razium-40 DSR Capsule is available for monopoly-based PCD pharma franchise across India and for third-party manufacturing under your brand. WHO-GMP certified, with full visual-aid and promotional support. Become a Trumac franchise partner →
Frequently Asked Questions
What is Razium-40 DSR Capsule used for?
Razium-40 DSR Capsule contains Rabeprazole 40 mg + Domperidone 30 mg (Sustained Release). Used as per the indications described above.
How should Razium-40 DSR Capsule be taken?
As directed by your physician. Complete the prescribed course.
Is Razium-40 DSR Capsule available for PCD pharma franchise?
Yes, Trumac Healthcare offers Razium-40 DSR Capsule on monopoly-based PCD pharma franchise and for third-party manufacturing.
How should Razium-40 DSR Capsule be stored?
Store below 30 °C in a dry place, protected from light and moisture.
Is Razium-40 DSR Capsule WHO-GMP certified?
Yes, manufactured in WHO-GMP and DCGI-compliant facilities.
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