Phenyrest-100 Tablet
Phenytoin 100 mg Tablets — Classical AED
| Composition | Phenytoin 100 mg |
|---|---|
| Dosage Form | Tablet |
| Pack Type | Alu-Alu Blister |
| Pack Size | 10 x 10 Tablets |
| MRP | ₹ 174 |
| Therapy | Neurology — Classical Sodium Channel Blocker AED |
| Storage | Store below 30 °C in a dry place, protected from light and moisture. |
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About Phenyrest-100 Tablet
Phenyrest-100 Tablet contains Phenytoin 100 mg — classical anti-epileptic for tonic-clonic and partial seizures. Long-established efficacy with significant drug interaction profile requires careful monitoring.
Standard maintenance: 300–400 mg/day in adults, with serum monitoring (target 10–20 mcg/ml).
Manufactured by Trumac Healthcare under WHO-GMP. Available for monopoly-based PCD pharma franchise and third-party manufacturing.
Indications
- Tonic-clonic seizures
- Complex partial seizures
- Status epilepticus (IV form)
- Trigeminal neuralgia (selected)
Mechanism of Action
Phenytoin (Diphenylhydantoin) is a sodium channel blocker — stabilises neuronal membranes by binding inactivated state of voltage-gated sodium channels, preventing high-frequency repetitive firing. Narrow therapeutic index (serum 10–20 mcg/ml). Non-linear pharmacokinetics.
Dosage & Administration
Adults: 300–400 mg/day, monitor serum levels. Children: weight-based.
Side Effects
Gingival hyperplasia, hirsutism, coarse facies, ataxia, nystagmus (at toxic levels), megaloblastic anaemia (folate deficiency), osteomalacia (Vit D deficiency), Stevens-Johnson syndrome (HLA-B*1502 carriers).
Contraindications & Precautions
Sinus bradycardia, heart block, hypersensitivity to hydantoins, porphyria.
Storage
Store below 30 °C in a dry place, protected from light and moisture.
Phenyrest-100 Tablet is available for monopoly-based PCD pharma franchise across India and for third-party manufacturing under your brand. WHO-GMP certified, with full visual-aid and promotional support. Become a Trumac franchise partner →
Frequently Asked Questions
What is Phenyrest-100 Tablet used for?
Phenyrest-100 Tablet contains Phenytoin 100 mg. Used as per the indications described above.
How should Phenyrest-100 Tablet be taken?
As directed by your physician. Complete the prescribed course.
Is Phenyrest-100 Tablet available for PCD pharma franchise?
Yes, Trumac Healthcare offers Phenyrest-100 Tablet on monopoly-based PCD pharma franchise and for third-party manufacturing.
How should Phenyrest-100 Tablet be stored?
Store below 30 °C in a dry place, protected from light and moisture.
Is Phenyrest-100 Tablet WHO-GMP certified?
Yes, manufactured in WHO-GMP and DCGI-compliant facilities.
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