Itrabin Cream

Itraconazole 1% + Terbinafine 1% — Dual Antifungal

Itrabin Cream — Itraconazole 1% + Terbinafine 1% Cream from Trumac Healthcare PCD Pharma Franchise India

Composition Itraconazole 1% + Terbinafine 1% Cream
Dosage Form Cream
Pack Type Tube
Pack Size 15gm
MRP ₹ 95
Therapy Derma — Topical triazole + allylamine dual antifungal
Storage Store below 25°C.

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About Itrabin Cream

Itrabin Cream combines the triazole Itraconazole 1% with the allylamine Terbinafine 1% in a single topical preparation. The two classes act on different steps of fungal ergosterol biosynthesis, producing additive activity against recalcitrant dermatophyte infections.

It is indicated for recalcitrant tinea corporis, tinea cruris, tinea pedis and pityriasis versicolor — particularly cases that have failed monotherapy with topical azoles or allylamines.

Camrut Healthcare manufactures Itrabin Cream under WHO-GMP conditions for PCD pharma franchise across India.

Indications

  • Recalcitrant tinea corporis or cruris
  • Tinea pedis (moccasin or interdigital)
  • Pityriasis versicolor
  • Mixed dermatophyte and Candida infections

Mechanism of Action

Itraconazole inhibits fungal 14-α-demethylase, blocking conversion of lanosterol to ergosterol. Terbinafine inhibits squalene epoxidase (earlier in the pathway), causing intracellular squalene accumulation which is directly fungicidal. The dual blockade at two enzymatic steps provides additive and synergistic activity.

Dosage & Administration

['Apply a thin layer to affected area 1–2 times daily', 'Continue for 2–4 weeks', 'Treat for 1 week beyond symptom resolution']

Side Effects

['Local burning or stinging', 'Skin redness', 'Contact dermatitis (rare)']

Contraindications & Precautions

['Hypersensitivity to triazoles or allylamines', 'Eye contact', 'Open wounds']

Storage

Store below 25°C.

PCD Pharma Franchise & Third-Party Manufacturing
Itrabin Cream is available for monopoly-based PCD pharma franchise across India and for third-party manufacturing under your brand. WHO-GMP certified, with full visual-aid and promotional support. Become a Trumac franchise partner →

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B2B Disclaimer: This page is part of a Business-to-Business (B2B) pharmaceutical catalog intended for distributors, PCD franchise partners and healthcare professionals. Information provided is for commercial and educational reference only. Not for consumer sale. Patients must not self-medicate; please consult a qualified medical practitioner. All trade inquiries are subject to valid Drug License and GST documentation.