Rumagard-S 375 mg Injection
Ceftriaxone 250 mg + Sulbactam 125 mg Injection
| Composition | Ceftriaxone 250 mg + Sulbactam 125 mg |
|---|---|
| Dosage Form | Injection (Vial) |
| Pack Type | Vial + Diluent |
| Pack Size | 1 Vial Pack |
| MRP | ₹ 75 |
| Therapy | G.P. / Paediatrics — Cephalosporin + BLI |
| Storage | Store 2–25 °C, protect from light. |
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About Rumagard-S 375 mg Injection
Rumagard-S 375 mg Injection combines Ceftriaxone 250 mg with Sulbactam 125 mg — for infections with beta-lactamase-producing organisms in children or low-dose adult use.
Manufactured by Trumac Healthcare under WHO-GMP. Available for monopoly-based PCD pharma franchise and third-party manufacturing.
Indications
- Paediatric infections with BL-producers
- Mild adult infections requiring BL-inhibitor coverage
Mechanism of Action
Ceftriaxone is a third-generation cephalosporin with broad gram-negative and gram-positive activity — binds penicillin-binding proteins (PBPs) inhibiting cell wall synthesis. Once-daily dosing due to long half-life (~8 hours). Penetrates CSF effectively making it first-line for meningitis. Sulbactam is a beta-lactamase inhibitor — protects Ceftriaxone from bacterial enzymatic hydrolysis, extending coverage against beta-lactamase-producing strains.
Dosage & Administration
Children: 50–80 mg/kg/day. Adults: 375 mg–1.5 g twice daily.
Side Effects
GI upset, diarrhoea (C. difficile risk), hypersensitivity (cross-reactivity with penicillins ~5%), biliary sludging (especially with calcium-containing IV fluids in neonates), rare haemolytic anaemia.
Contraindications & Precautions
Cephalosporin/penicillin hypersensitivity, neonates with hyperbilirubinaemia, concurrent calcium IV in neonates (Ringer's lactate).
Storage
Store 2–25 °C, protect from light.
Rumagard-S 375 mg Injection is available for monopoly-based PCD pharma franchise across India and for third-party manufacturing under your brand. WHO-GMP certified, with full visual-aid and promotional support. Become a Trumac franchise partner →
Frequently Asked Questions
What is Rumagard-S 375 mg Injection used for?
Rumagard-S 375 mg Injection contains Ceftriaxone 250 mg + Sulbactam 125 mg. Used as per the indications described above.
How should Rumagard-S 375 mg Injection be taken?
As directed by your physician. Complete the prescribed course.
Is Rumagard-S 375 mg Injection available for PCD pharma franchise?
Yes, Trumac Healthcare offers Rumagard-S 375 mg Injection on monopoly-based PCD pharma franchise and for third-party manufacturing.
How should Rumagard-S 375 mg Injection be stored?
Store below 30 °C in a dry place, protected from light and moisture.
Is Rumagard-S 375 mg Injection WHO-GMP certified?
Yes, manufactured in WHO-GMP and DCGI-compliant facilities.
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