Bi-Folitic Tablet
Biotin 5 mg + Methylcobalamin 1500 mcg + L-Methylfolate 1 mg Tablets — Methylated B-Vitamins
| Composition | Biotin 5 mg + Methylcobalamin 1500 mcg + L-Methylfolate 1 mg |
|---|---|
| Dosage Form | Tablet |
| Pack Type | Alu-Alu Blister |
| Pack Size | 10 x 10 Tablets |
| MRP | ₹ 1890 |
| Therapy | Gynaecology + G.P. — Methylated B-Vitamin Combination |
| Storage | Store below 30 °C in a dry place, protected from light and moisture. |
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About Bi-Folitic Tablet
Bi-Folitic Tablet combines three biologically active (methylated) B-vitamins: Biotin 5 mg, Methylcobalamin 1500 mcg and L-Methylfolate 1 mg. Unlike folic acid and cyanocobalamin (which require enzymatic conversion to the active forms), these methylated forms are immediately bioavailable — beneficial for patients with MTHFR gene polymorphisms (common in Indian populations) that reduce folate metabolism efficiency.
Clinically, Bi-Folitic is used in hair fall, brittle nails, hyperhomocysteinaemia, peripheral neuropathy, methylation defects and pre-conception folate supplementation. The combination supports DNA synthesis, neurotransmitter formation and myelin integrity — all of which depend on functional one-carbon (methylation) metabolism.
Bi-Folitic is manufactured by Trumac Healthcare under WHO-GMP and FSSAI compliant conditions. Available for monopoly-based PCD pharma franchise and third-party manufacturing — a high-margin specialty SKU.
Indications
- Hair fall, brittle nails and biotin deficiency
- Hyperhomocysteinaemia and methylation defects
- Peripheral neuropathy (with diabetes or B12 deficiency)
- Pre-conception and early pregnancy folate supplementation
- MTHFR polymorphism-associated reduced folate metabolism
- Adjunct in depression with high homocysteine
Mechanism of Action
L-Methylfolate is the bioactive form of folate that crosses the blood-brain barrier and serves as methyl donor for neurotransmitter and DNA methylation. Methylcobalamin is the active form of B12 that regenerates methionine from homocysteine. Biotin is a cofactor for carboxylase enzymes in fatty acid synthesis and metabolism, critical for hair keratin and nail formation.
Dosage & Administration
Adults: 1 tablet once daily, preferably after a meal, or as directed by a physician. Long-term continuation in chronic deficiency or pre-conception planning.
Side Effects
Generally well tolerated. Possible mild GI upset, headache. Biotin at very high doses can interfere with biotin-based lab assays (e.g., thyroid, troponin) — inform your lab if testing. Rare hypersensitivity.
Contraindications & Precautions
Hypersensitivity to any component. Caution with concomitant anticonvulsants (folate may reduce levels of some). Pernicious anaemia (use injectable B12 if oral inadequate).
Storage
Store below 30 °C in a dry place, protected from light and moisture.
Bi-Folitic Tablet is available for monopoly-based PCD pharma franchise across India and for third-party manufacturing under your brand. WHO-GMP certified, with full visual-aid and promotional support. Become a Trumac franchise partner →
Frequently Asked Questions
What is Bi-Folitic Tablet used for?
Bi-Folitic supplies the active forms of three B-vitamins — Biotin, Methylcobalamin and L-Methylfolate — for hair fall, peripheral neuropathy, hyperhomocysteinaemia, pre-conception folate and methylation support.
Why methylated B-vitamins?
Around 30–50% of people have MTHFR gene variants that reduce folate metabolism. Methylated forms bypass this step and are immediately bioavailable, particularly valuable in pre-conception care and methylation defects.
Is Bi-Folitic available for PCD pharma franchise?
Yes, Trumac Healthcare offers Bi-Folitic on monopoly-based PCD pharma franchise and for third-party manufacturing.
How should Bi-Folitic Tablet be stored?
Store below 30 °C in a dry place, away from direct sunlight and moisture.
Is Bi-Folitic WHO-GMP certified?
Yes, manufactured in WHO-GMP and FSSAI compliant facilities.
Related Products
- Becowise Capsule — Vitamin B1 2.3mg + B2 3.2mg + B6 2.4mg + B12 + Pantothenic Acid + Niacinamide (multi-B-vitamin combination)
- Becowise-Forte Tablet — Thiamine 1.7 mg + Nicotinamide 14 mg + Calcium Pantothenate + Pyridoxine + Cyanocobalamin (high-strength B-complex)
- Arginep-Plus Sachets — L-Arginine 3 g + Folic Acid 1.5 mg + Methylcobalamin 1500 mcg + Zinc 4 mg per sachet